EAPM COURSE

Complicated monochorionic twins: TTS, TAPS, sFGR

Coordinators: Enrico Lopriore and Sophie Groene (the Netherlands)

Enrolment is limited to 75 participants only.
Registration fee: 65 € (plus 22% VAT)

Course Overview

 

Monochorionic (MC) twins are connected by vascular anastomoses within the single shared
placenta and may develop complications such as twin-twin transfusion syndrome (TTS), twin
anemia polycythemia sequence (TAPS) and selective intrauterine growth restriction (sFGR). All
these complications carry a high risk of fetal morbidity and mortality if not timely diagnosed
and/or not appropriately managed.

The purpose of this course is to summarize the current evidence on optimal management for each
specific type of MC twin complications in a structured and clear manner. We will provide
participants essential tips and tricks to reach the correct diagnosis, explain the challenges of the
different treatment options and highlight the short and long-term outcomes which can be used to
counsel parents appropriately.

Target audience

Neonatologists, obstetricians, perinatologists, pediatricians, ultrasonographists

Course programme

14:00 – 14:15 Introduction

  • Introduction and objectives (10min) – Enrico Lopriore
  • Interactive survey (5min) – Sophie Groene

14:15-14:30 Monochorionic twins: a general overview – Mariano Lanna

14:30-15:10 Selective Fetal Growth Restriction (sFGR)

  • Diagnosis and antenatal management – Liesbeth Lewi
  • Neonatal management – Enrico Lopriore
  • Long-term outcome  – Sophie Groene
  • Case discussion – Asma Khalil
  • Questions

15:10-15:30 Break  

15:30-16:10 Twin-Twin Transfusion Syndrome (TTTS) 

  • Diagnosis and antenatal management – Femke Slaghekke
  • Neonatal management – Enrico Lopriore
  • Long-term outcome – Jeanine van Klink
  • Case discussion – Asma Khalil
  • Questions

16:10-16:20 Break 

16:20-17:00 Twin Anemia Polycythemia Sequence (TAPS)

  • Diagnosis and antenatal management – Lisanne Tollenaar
  • Neonatal management – Enrico Lopriore
  • Long-term outcome – Jeanine van Klink
  • Case discussion – Asma Khalil
  • Questions

17:00-17:15 Discussion with participants

Enrico Lopriore

, MD, PhD​

Leiden, The Netherlands​

is a professor of neonatology and fetal medicine and head of the Neonatal Intensive Care Unit at the Leiden University Medical Center (LUMC).

Neonatology and fetal medicine
His research focuses mainly on the origin, management and outcome in various fetal disorders, including complicated monochorionic twins (with TTS, TAPS or sIUGR) and fetal hematologic diseases (anemia or thrombocytopenia). The ultimate goal of his research is to improve perinatal survival and in particular the long-term outcome in these vulnerable babies.

Academic career
Enrico Lopriore absolved Medical School and his doctoral research at Leiden University. The title of his doctoral thesis (2006) reads ‘Twin-to-twin transfusion syndrome: from placental anastomoses to long-term outcome’. He was appointed Professor in Neonatology of the Leiden University Medical Center in July 2016. The title of his inaugural lecture was ‘Blood brothers‘.

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